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	Provedor de dados BJMBR (5) Autor Dib,S.A. (5) Silva,R.C. (2) Sá,J.R. (2) Aguade,L.C.M. (1) Atallah,A.N. (1) Castro,A.A. (1) Chacra,A.R. (1) Faiçal,S. (1) Falorni,A. (1) Fernandes,V.T. (1) Giuffrida,F.M.A. (1) Guedes,O.M.S. (1) Kater,C.E. (1) Laureti,S. (1) Mourão-Júnior,C.A. (1) Nasri,F. (1) Velloso,L. (1) Verreschi,I.T.N. (1) Mais... Palavra-chave Addison's disease (1) Adrenal gland (1) Autoantibodies detection (1) Beta cell function (1) Blood pressure (1) Brazilian type 1 diabetes (1) Cholesterol (1) Diabetes (1) Diet therapy (1) Fetal macrosomia (1) Gestational (1) Growth and development (1) Indirect immunofluorescence (1) Insulin (1) Insulin sensitivity (1) Islet cell antibodies (1) Meta-analysis (1) Metabolic syndrome (1) Metformin (1) Non-insulin-dependent diabete mellitus (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Info:eu-repo/semantics/other (1) Ano 2006 (1) 2003 (2) 2001 (1) 1998 (1) País Brazil (5) Idioma Inglês (5)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última Detection of adrenocortical autoantibodies in Addison's disease with a peroxidase-labelled protein A technique BJMBR Silva,R.C.; Faiçal,S.; Laureti,S.; Falorni,A.; Dib,S.A.; Kater,C.E.. Adrenocortical autoantibodies (ACA), present in 60-80% of patients with idiopathic Addison's disease, are conventionally detected by indirect immunofluorescence (IIF) on frozen sections of adrenal glands. The large-scale use of IIF is limited in part by the need for a fluorescence microscope and the fact that histological sections cannot be stored for long periods of time. To circumvent these restrictions we developed a novel peroxidase-labelled protein A (PLPA) technique for the detection of ACA in patients with Addison's disease and compared the results with those obtained with the classical IIF assay. We studied serum samples from 90 healthy control subjects and 22 patients with Addison's disease, who had been clinically classified into two groups:... Tipo: Info:eu-repo/semantics/article Palavras-chave: Autoantibodies detection; Addison's disease; Peroxidase-labelled protein A; Indirect immunofluorescence; Adrenal gland. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000900007 Development according to pubertal stage in Brazilian children and adolescents with short-term diabetes BJMBR Fernandes,V.T.; Verreschi,I.T.N.; Dib,S.A.. The anthropometric status and metabolic control of 51 recently diagnosed Brazilian schoolchildren with type 1 diabetes (DM1), during the first 5 years of the disease, were compared with those of normal children (60 girls and 132 boys) belonging to the same environmental condition and pubertal stage. Metabolic control was evaluated on the basis of fasting plasma glucose (FPG) and HbA1c levels. The criteria of the National Center for Health Statistics were used for anthropometric evaluation. FPG (205 ± 51 mg/dl for girls vs 200 ± 34 mg/dl for boys) and % above upper normal limit of median HbA1c (1.8% for girls vs 2.5% for boys with diabetes) were not significantly different during follow-up. The Z-score of the last height evaluation was lower in the girls'... Tipo: Info:eu-repo/semantics/article Palavras-chave: Brazilian type 1 diabetes; Growth and development; Pubertal stage. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000012 Diet plus insulin compared to diet alone in the treatment of gestational diabetes mellitus: a systematic review BJMBR Giuffrida,F.M.A.; Castro,A.A.; Atallah,A.N.; Dib,S.A.. Fetuses of mothers with gestational diabetes mellitus are at increased risk to develop perinatal complications mainly due to macrosomia. However, in view of the marked heterogeneity of this disease, it seems difficult to set guidelines for diagnosis and treatment. This complicates the choice of assigning patients either to diet or to insulin therapy. Also of concern is how much benefit could be expected from insulin therapy in preventing fetal complications in these patients. In a systematic review of the literature assessing the efficacy of insulin in preventing macrosomia in fetuses of mothers with gestational diabetes, we found six randomized controlled trials comparing diet alone to diet plus insulin. The studies included a total of 1281 patients (644... Tipo: Info:eu-repo/semantics/other Palavras-chave: Diabetes; Gestational; Diet therapy; Fetal macrosomia; Insulin; Meta-analysis. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000004 Effects of metformin on the glycemic control, lipid profile, and arterial blood pressure of type 2 diabetic patients with metabolic syndrome already on insulin BJMBR Mourão-Júnior,C.A.; Sá,J.R.; Guedes,O.M.S.; Dib,S.A.. Fifty-seven type 2 diabetic patients with metabolic syndrome and on insulin were assessed by a paired analysis before and 6 months after addition of metformin as combination therapy to evaluate the impact of the association on glycemic control, blood pressure, and lipid profile. This was a historical cohort study in which the files of type 2 diabetic patients with metabolic syndrome on insulin were reviewed. The body mass index (BMI), waist circumference, lipid profile, A1C level, fasting blood glucose level, daily dose of NPH insulin, systolic blood pressure, and diastolic blood pressure were assessed in each patient before the start of metformin and 6 months after the initiation of combination therapy. Glycemic control significantly improved (P <... Tipo: Info:eu-repo/semantics/article Palavras-chave: Type 2 diabetes mellitus; Metabolic syndrome; Metformin; Blood pressure; Cholesterol; Triglycerides. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000400009 Non-obese adult onset diabetes with oral hypoglycemic agent failure: islet cell autoantibodies or reversible beta cell refractoriness? BJMBR Sá,J.R.; Silva,R.C.; Nasri,F.; Aguade,L.C.M.; Velloso,L.; Chacra,A.R.; Dib,S.A.. Pancreatic ß cell function and insulin sensitivity, analyzed by the homeostasis model assessment, before and after 24 weeks of insulin therapy were studied and correlated with the presence of autoantibodies against ß cells (islet cell and anti-glutamic acid decarboxylase antibodies), in a group of 18 Brazilian lean adult non-insulin-dependent diabetes mellitus (NIDDM) patients with oral hypoglycemic agent failure (OHAF). Median fasting plasma glucose before and after insulin treatment was 19.1 and 8.5 mmol/l, respectively (P < 0.001); median HbA1c was 11.7% before vs 7.2% after insulin treatment (P < 0.001). Forty-four percent of the patients were positive (Ab+) to at least one autoantibody. Fasting C-peptide levels were lower in Ab+ than Ab-... Tipo: Info:eu-repo/semantics/article Palavras-chave: Non-obese diabetes mellitus; Oral hypoglycemic agent failure; Non-insulin-dependent diabete mellitus; Islet cell antibodies; Beta cell function; Insulin sensitivity. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000005 Registros recuperados: 5 Primeira ... 1 ... Última

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